Illustrative estimate only - not verified by this sponsor. Contact the study team for actual compensation.
The specific objective of this proposed research is to understand whether deficits in sleep-dependent memory changes reflect age-related changes in sleep, memory, or both. The central hypothesis is that changes in both memory and sleep contribute to age-related changes in sleep-dependent memory processing. To this end, the investigators will investigate changes in learning following intervals of sleep (overnight and nap) and wake in young and older adults.
What happens when you apply
Reach out via phone or email to express interest
Brief call to discuss your health history
Medical screening at the research site
Begin your journey in the study
Inclusion Criteria: * Age 18-80 yrs * Healthy sleeper * No diagnosed sleep or neurodegenerative disorder Exclusion Criteria: 1. Past diagnosis of any sleep disorder or evidence of a sleep disorder as assessed by self-reported sleep quality assessments, a standardized diagnostic interview, and an acclimation night of polysomnography. Using acclimation-night polysomnography, participants will be excluded with an Apnea-Hypopnea Index \>15; a Period-Limb Movement in Sleep index of \>15/hr; sleep-onset latency \> 45 min (indicative of insomnia); or sleep efficiency \< 80% (see Edinger et al., Sleep, 2004). In cases in which questions arise regarding a participants' inclusion or sleep records, a practicing neurologist board-certified in sleep medicine will review the documentation. 2. Past diagnosis neurological illness or head injury 3. Reported average sleep per night \< 5 or \> 9 hrs 4. Current employment involving shift work or an inability to keep a regular sleep schedule during the week prior to testing 5. Current use of psychotropic, recreational drugs, or sleep-altering medications (sleep medications, cold medicines within the past week, clonidine, sympathomimetic stimulants) 6. Daily caffeine intake of \> 4 cups (coffee, tea, colas) 7. Weekly alcohol intake of \> 10 cups 8. Pregnancy or \< 12 months post-partum 9. History of bipolar disorder, mania, or current evidence of depression as measured by Beck Depression Inventory score \> 25 10. Abnormal sleep (e.g., shift work, travel across \>2 time zones within the past 3 months). 11. Diagnosis of any Axis I disorder, neurological illness or head injury (according to Demographic and Health History form); 12. Score indicative of cognitive dysfunction (subtest scores \< 40) 13. Beck Depression Scale score indicative of depression (\> 19). Additionally, individuals will be excluded from magnetic resonance imaging studies (Exps 1, 4) for: 1. Left handed or ambidextrous 2. Claustrophobia 3. Presence of metal (thoroughly screened via questionnaire and metal detector) 4. Pregnancy
imaguineapig pulls live data from ClinicalTrials.gov (NIH/NLM).Illustrative estimate only - not verifiedPay estimates are approximate ranges based on study type and are not confirmed by sponsors — actual compensation may differ. Eligibility indicators use limited criteria (age, sex) only. We do not provide medical advice. Always contact the study team directly to confirm compensation, full eligibility, and risks before enrolling.