Illustrative estimate only - not verified by this sponsor. Contact the study team for actual compensation.
A large proportion of pregnant women develop pregnancy-related low back and/or pelvic girdle pain (PPGP), which often does not recover spontaneously postpartum. As a result, 10% of women with PPGP are thus crucial. However, the underlying mechanisms of PPGP are still poorly understood. The main objective of this study is to investigate whether lumbar proprioceptive deficits, a disturbed body perception at the lumbar spine, psychosocial factors (incl. pain-related fear of movement, depression, anxiety and stress) and increased serum concentrations of specific inflammatory mediators are associated with (1) a reduced postural control and (2) the development and/or persistence of PPGP in multiparous women during the first and third trimester of pregnancy, and six weeks and six months postpartum.
What happens when you apply
Reach out via phone or email to express interest
Brief call to discuss your health history
Medical screening at the research site
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Inclusion Criteria Multiparous Women: * Singleton pregnancy * Pregnant of second child or more than second child * No current PPGP or did not have PPGP during current pregnancy * Willing to provide written informed consent Exclusion Criteria Multiparous Women: * Pregnant for more than 16 weeks * Having current PPGP or having had PPGP during the current pregnancy * History of surgery/major trauma to spine or pelvis * Surgery/physical trauma to the lower limbs more than two years ago and currently still experiencing symptoms such as pain, instability, or stiffness * Surgery/physical trauma to the lower limbs less than two years ago * Specific balance or vestibular disorders * A medical diagnosis of a rheumatic condition or being under treatment for such a condition by a rheumatologist * Neurological abnormalities (e.g., peripheral neuropathy) * Uncorrected visual problems * Acute ankle problems * Being on absolute or relative bed rest due to pregnancy-related complications * Having (had) a formal diagnosis of a psychiatric disorder * Non-Dutch speaking Inclusion Criteria Nulliparous Women: * Age- and BMI- matched to pregnant participants * Nulliparous * Willing to provide written informed consent Exclusion Criteria Nulliparous Women: * Having low back or pelvic girdle pain at the time of inclusion or in the six months leading up to inclusion * History of chronic low back or pelvic girdle pain * History of surgery/major trauma to spine, pelvis and/or lower limbs, * Specific balance or vestibular disorders * Spinal deformities * Rheumatic disease * Neurological abnormalities * Acute ankle problems * (A history of) psychiatric disorders * Uncorrected visual problems * Non-Dutch speaking
imaguineapig pulls live data from ClinicalTrials.gov (NIH/NLM).Illustrative estimate only - not verifiedPay estimates are approximate ranges based on study type and are not confirmed by sponsors — actual compensation may differ. Eligibility indicators use limited criteria (age, sex) only. We do not provide medical advice. Always contact the study team directly to confirm compensation, full eligibility, and risks before enrolling.