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Developing a Clinical Outcome Assessment for Opioid Craving

Sponsor

Johns Hopkins University

Pharma

Typical Pay Range

$50 – $1,000

Illustrative estimate only - not verified by this sponsor. Contact the study team for actual compensation.

About This Study

The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disorder. To collect this information, the investigators are recruiting individuals in treatment for opioid use disorder who will complete cue-induced opioid craving tasks where these individuals will: (1) look at pictures of neutral objects and touch neutral objects (e.g., water bottles or flashlights), (2) look at opioid-related images, and (3) look and touch opioid-related objects. Participants will then complete a one-on-one interview about the thoughts, feelings and physical sensations the participants experienced during the cue-induced craving session. Participants will also complete questionnaires and existing opioid craving assessments. Finally, participants will provide formal feedback about existing opioid craving assessments with cognitive interviews.

Your Journey

What happens when you apply

📞

Contact Study Team

5 min

Reach out via phone or email to express interest

💬

Phone Screening

15-30 min

Brief call to discuss your health history

🏥

In-Person Visit

2-4 hours

Medical screening at the research site

🚀

Start Participation

Varies

Begin your journey in the study

Questions to Ask

What's the exact compensation schedule?

What are the potential side effects?

Can I withdraw at any time?

Phase

N/A

Enrollment

81 participants

Sites

1 location

Timeline

Mar 2022 - Sep 2026

What's Involved

Neutral Cue-induced CravingVisual Opioid Cue-induced CravingVisual and Tactile Opioid Cue-induced Craving

Conditions Studied

Opioid CravingOpioid Use DisorderMeasure Development

Study Locations

Behavioral Pharmacology Research Unit

Baltimore, Maryland, United States

Eligibility

Min Age:18 Years

Sex:ALL

Full Criteria

Inclusion Criteria:

* 18 years of age and older
* Opioid-positive urine sample at admission visit (excluding individuals receiving Naltrexone).
* Current opioid use disorder per Diagnostic Statistical Manual (DSM)-5
* Currently in treatment for opioid use disorder

Exclusion Criteria:

* Being pregnant or breastfeeding, or may become pregnant during the trial
* History of psychosis or mania or other serious psychiatric disorders assessed by the Mini International Neuropsychiatric Interview
* Past 30-day suicidal behavior assessed by the Columbia Suicide Severity Rating Scale
* Have circumstances that would interfere with study participation (e.g., impending jail).
* Positive for illicit substances except opioids and cannabis
* Current substance use disorder other than opioid or nicotine
* Current intoxication

NCT05109429

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Trials by City

Baltimore, Maryland

imaguineapig pulls live data from ClinicalTrials.gov (NIH/NLM).Illustrative estimate only - not verifiedPay estimates are approximate ranges based on study type and are not confirmed by sponsors — actual compensation may differ. Eligibility indicators use limited criteria (age, sex) only. We do not provide medical advice. Always contact the study team directly to confirm compensation, full eligibility, and risks before enrolling.