Illustrative estimate only - not verified by this sponsor. Contact the study team for actual compensation.
The study investigates the role of mTOR in mediating enhancement of muscle insulin sensitivity following a single bout of exercise. This will be investigated in young healthy male subjects by administering the pharmacological mTOR inhibitor Rapamycin in a crossover blinded experimental setup known to enhance muscle insulin sensitivity following one-legged knee-extensor exercise.
What happens when you apply
Reach out via phone or email to express interest
Brief call to discuss your health history
Medical screening at the research site
Begin your journey in the study
Inclusion Criteria: * Healthy persons (no known disease) without diabetes in the family * No use of medications * Non-smokers * Men * Age 22-35 years * Physical activity level (VO2peak) between 30-50 mL O2/min/kg * BMI between 18.0 and 25.0 Exclusion Criteria: * Women * Physical activity (e.g., running, cycling, fitness, etc.) above 6 hours a week. * Persons who show signs of metabolic diseases, hematologic diseases, reduced liver function, human immunodeficiency virus (HIV), hepatitis, thyroid diseases or other signs of disease that may affect the outcome of the study or the study subject's wellbeing will be excluded. * Acute sickness less than 2 weeks prior to study start. * If disease appears or is identified and/or a need for medication arises after inclusion but before initiation of the study. Disease during conclusion of the study
imaguineapig pulls live data from ClinicalTrials.gov (NIH/NLM).Illustrative estimate only - not verifiedPay estimates are approximate ranges based on study type and are not confirmed by sponsors — actual compensation may differ. Eligibility indicators use limited criteria (age, sex) only. We do not provide medical advice. Always contact the study team directly to confirm compensation, full eligibility, and risks before enrolling.